Chemical and Biological Investigation of Sanchezia nobilis Leaves Extract

The project work was designed to investigate the phytochemical and selected pharmacological activities (anti-diarrheal, analgesic, neuropharmacological behavior anthelmintic) of leaves Sanchezia nobilis. Hook. F. (Family: Acanthaceae). From its analysis we found presence reducing sugar, combined phenolic compounds, tannins, flavonoids, carbohydrates, gums, steroids, alkaloids, glycosides terpenoids. In vivo antidiarrheal activity substantiated by prolongation latent period decrease in total number stools. extract produced 62.49% 74.01% stool count at doses 250 500 mg/kg body weight respectively while standard drug Loperamide be 87.05% a dose 3 weight. 32.7% 41.78% inhibition writhing Diclofenac Na 74.23% 25 showed dependent CNS depressant locomotors activity. Higher this (500 weight) comparing with Diazepam exposed sedative effect potentially. exhibited concentration anthelmintic against Paramphistomum cervi using Albendazole (15 mg/mL) as standard. paralysis occurred between 9.00 83.91 min death 11.33 86.33 which were comparable Albendazole. So, present study concluded that is fortified significant antidiarrheal, depression moderate analgesic